You can find here all events related to the GDR. For some of these, if you want to participate, you will have to fill a register form at the bottom of the description.
GDR meeting November 6th-9th, 2020
The 9th GDR3545-GPCR international meeting will be held on-line from November 6th to 9th 2020.
Eight sessions: Signaling networks - Compartmentalized signaling - Drug discovery - Metabolism & microbiome - Neurobiology & sensory biology - Structural biology and Computational approaches. A panel of outstanding speakers:
Registration is compulsory (Academia: free; Industry: 200€). Scientific program, online registration and abstract submission available at
For students and early carrier investigators: 3 minutes flash presentations and posters will be selected from submitted abstracts (deadline for abstract submission: October 15th, 2020). F
ive 500€ poster prizes will be awarded. A workshop dedicated to students and early career investigators will be held on November 5th, 2020.
The 2020 GDR organizing committee looks forward to your participation to the next GDR3545-GPCR meeting in November 2020!
14.00-14.10 Welcome message – Opening
Session 1: Signaling networks Chair: Hélène Castel-Gandolfo & Séverine Morisset-Lopez
14.10-14.30 Nevin Lambert (Augusta University, USA): Unconventional GPCR-G protein coupling
14.30-14.50 RB Russell (Heidelberg University, Germany): Illuminating G protein-coupling selectivity
14.50-15.10 Laurent Prezeau (IGF, Montpellier, France): Nonclassical Ligand-Independent Regulation of Go Protein by an Orphan Class C G-Protein-Coupled Receptor
15.10-15.30 Ralf Jockers, (Institut Cochin, France), GPR50-Ctail cleavage and nuclear translocation: a new signal transduction mode for G protein-coupled receptors
15.30-15.45 Flash presentations 1 (5 x 3’ talks)
15.45-16.10 Chat rooms session 1
Session 2: Compartmentalized signaling Chair: Romain Yvinec & Frédéric Jean-Alphonse
16.10-16.30 JP Vilardaga (Pittsburg, USA) PTHR location biased signaling (endosomal vs membrane signaling) and in vivo consequences
16.30-16.50 Miriam Stoeber (University of Geneva, Switzerland) Location bias signaling (endosomes, golgi)
16.50-17.10 Séverine Chaumont-Dubel (IGF, Montpellier, France): Dynamic interactions of the 5-HT6 receptor with protein partners control dendritic tree morphogenesis
17.10-17.30 Grégoire Vandecasteele (Inserm Paris-Sud) PDE4 and mAKAPβ are nodal organizers of β2-ARs nuclear PKA signaling in cardiac myocytes
17.30-17-45 Flash presentations 2 (5 x 3’ talks)
17.45-18.10 Chat rooms session 2
18.10-19.00 Keynote lecture 1: Michel Bouvier (Université de Montréal, Canada)
Session 3: Drug discovery I Chair: Hélène Castel-Gandolfo & Frédéric Jean-Alphonse
14.00-14.20 Rachel Friedman Ohana, (Pomega corporation, USA) TBD
14.20-14.40 Laura Bohn (Scripps, USA) Toward Directing Opioid Receptor Signaling to Refine Opioid Therapeutics
14.40-15.00 Jean-Marc Devaud (Toulouse, France) Targeting an allatostatin receptor, a potential mediator of stress response in honey bees
15.00-15.20 Jean-Luc Galzi
15.20-15.35 Flash presentations 3 (5 x 3’ talks)
15.35-16.00 Chat rooms session 3
Session 4: Drug discovery II Chair: Séverine Morisset-Lopez & Eric Reiter
16.00-16.20 Ross Cheloha (Harvard, Boston, USA) Nanobody-drug-conjugate at PTHR
16.20-16.40 S.J. Hill (University of Nottingham,UK) CRISPR-Mediated Protein Tagging with Nanoluciferase to Investigate Native Chemokine Receptor Function and Conformational Changes
16.40-17.00 Philippe Rondard (IGF, Montpellier, France) Nanobodies mGluR
17.20-17.35 Flash presentations 4 (5 x 3’ talks)
17.35-18.00 Chat rooms session 4
18.00-18.50 Keynote lecture 2
Bryan L. Roth (Univ North Carolina, USA)
Session 5: Metabolism, Microbiome Chair: Pablo Chamero & Eric Reiter
14.00-14.20 Thue W Schwartz (The Panum Institute, Copenhagen, Denmark) Enterochromaffin 5-HT Cells - A Major Target for GLP-1 and Gut Microbial Metabolites
14.20-14.40 Graeme Milligan (University of Glasgow, Glasgow, UK) Short chain free fatty acids receptor
14.40-15.00 François Trottein (Pasteur Lille, France) Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production
15.00-15.20 Jacques Pantel (INSERM, Paris, France) Input of ghrelin receptor mutations in today’s understanding of the ghrelin system
15.20-15.35 Flash presentations 5 (5 x 3’ talks)
15.35-16.00 Chat rooms session 5
Session 6: Neurobiology, sensory biology Chair: Lucie Pellissier & Pablo Chamero
16.00-16.20 Hiro Matsunami (Duke University, USA): Odorant receptors
16.20-16.40 Jianfeng Liu (or somebody from his lab) (Wuhan, China) A Cold-Sensing Receptor Encoded by a Glutamate Receptor Gene
16.40-17.00 Christophe Rochais (Caen, France) 5HTR ligand and Alzheimer
17.00-17.20 Pascal Dournaud (INSERM, Paris, France) A simple novel approach for detecting blood-brain barrier permeability using GPCR internalization
17.20-17.35 Flash presentations 6 (5 x 3’ talks)
17.35-18.00 Chat rooms session 6
18.00-18.50 Keynote lecture 3
Valery Grinevich (Zentralinstitut für Seelische Gesundheit, Mannheim, Germany)
Session 7: Structural biology Chair : Pascale Crépieux & Anne Poupon
14.00-14.20 Martha Sommer
14.20-14.40 Martin J Lohse (Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany): Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement
14.40-15.00 Bernard Mouillac (IGF, Montpellier, France): Cryo-EM structure of the vasopressin hormone-V2 receptor-Gs protein ternary complex
15.00-15.20 Esther Kellenberger (University of Strasbourg, France): Structure function relationships of CCR5
15.20-15.35 Flash presentations 7 (5 x 3’ talks)
15.35-16.00 Chat rooms session 7
Session 8: Computational approaches Chair : Pascale Crépieux & Romain Yvinec
16.00-16.20 David E. Gloriam (University of Copenhagen, Copenhagen, Denmark) Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors
16.20-16.40 Graham Ladds ( University of Cambridge, UK) Engineering a Model Cell for Rational Tuning of GPCR Signaling
16.40-17.00 Romain Yvinec (INRAE Nouzilly, France) Mathematical modeling of GPCR-induced signaling.
17.00-17.20 Hughes Berry
17.20-17.35 Flash presentations 8 (5 x 3’ talks)
17.35-18.00 Chat rooms session 8
18.00-18.50 Keynote lecture 4
Brian Kobilka (Stanford University, USA)
18.50-19.50 Awards & conclusions
Scope of the 2020 Workshop: ‘bioinformatics and biomathematical approaches to integrate the GPCR signal’. Computational and mathematical approaches are nowadays compulsory in order to decipher the complexity of GPCR signalling networks. The workshop will focus on recent modelling and computational approaches and how they can be used to tackle GPCR complexity.
Virtual workshop on November 5th, 2020 from 1.30-5.30 pm. To register please fill the form at the bottom
Participants: max 20 GDR ECI + 20 ERNEST/IRN ECI
Chair-women: Erika Cecon and Lucie Pellissier
The purpose of this presentation will be to address how biomathematical approaches help deciphering kinetic and biased signalling.
Cytoscape is an open source platform to analyze omic data. A demonstration of its potential will be presented using the RFSH signalling network as an example.
The annual congress of the European Research Network on Signal Transduction (ERNEST) has invited the GDR-3545 to organize a virtual session with early career researchers from the GDR the 14th October from 10h45 to 12h05.
Link for registration: https://ernestcostaction.wixsite.com/website/event-details/third-ernest-meeting/form
Link for abstract submission: https://ernestcostaction.wixsite.com/website/abstract-submission
Cell Bio Virtual 2020 Registration
is Now Open!
Connect Virtually From Wherever You Are
ascb.org/cellbiovirtual2020 | #cellbio2020
The joint meeting of the American Society for Cell Biology (ASCB) and the European Molecular Biology Organization (EMBO) takes cell biology to the virtual stage. Taking place December 2-16, 2020, the meeting will maintain cutting-edge cell biology as its core focus, along with interdisciplinary programming—giving attendees a place to learn from and collaborate with top researchers in their specific research area.