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Events of the GDR 3545

You can find here all events related to the GDR. For some of these, if you want to participate, you will have to fill a register form at the bottom of the description.

9th GDR meeting November 6th-9th, 2020

on 25 September 2020

GDR meeting November 6th-9th, 2020


The 9th GDR3545-GPCR international meeting will be held on-line from November 6th to 9th 2020.

Eight sessions: Signaling networks - Compartmentalized signaling - Drug discovery - Metabolism & microbiome - Neurobiology & sensory biology - Structural biology and Computational approaches. A panel of outstanding speakers:


Registration is compulsory (Academia: free; Industry: 200€). Scientific program, online registration and abstract submission available at

For students and early carrier investigators: 3 minutes flash presentations and posters will be selected from submitted abstracts (deadline for abstract submission: October 15th, 2020). F

ive 500€ poster prizes will be awarded. A workshop dedicated to students and early career investigators will be held on November 5th, 2020.


The 2020 GDR organizing committee looks forward to your participation to the next GDR3545-GPCR meeting in November 2020!


Scientific program

Day 1

14.00-14.10        Welcome message – Opening

Session 1: Signaling networks                        Chair: Hélène Castel-Gandolfo & Séverine Morisset-Lopez

14.10-14.30        Nevin Lambert (Augusta University, USA): Unconventional GPCR-G protein coupling

14.30-14.50        RB Russell (Heidelberg University, Germany): Illuminating G protein-coupling selectivity

14.50-15.10        Laurent Prezeau (IGF, Montpellier, France): Nonclassical Ligand-Independent Regulation of Go Protein by an Orphan Class C G-Protein-Coupled Receptor

15.10-15.30        Ralf Jockers, (Institut Cochin, France), GPR50-Ctail cleavage and nuclear translocation: a new signal transduction mode for G protein-coupled receptors

15.30-15.45        Flash presentations 1 (5 x 3’ talks)

15.45-16.10        Chat rooms session 1

Session 2: Compartmentalized signaling                  Chair: Romain Yvinec & Frédéric Jean-Alphonse

16.10-16.30        JP Vilardaga (Pittsburg, USA) PTHR location biased signaling (endosomal vs membrane signaling) and in vivo consequences

16.30-16.50        Miriam Stoeber (University of Geneva, Switzerland) Location bias signaling (endosomes, golgi)

16.50-17.10        Séverine Chaumont-Dubel (IGF, Montpellier, France): Dynamic interactions of the 5-HT6 receptor with protein partners control dendritic tree morphogenesis

17.10-17.30        Grégoire Vandecasteele (Inserm Paris-Sud) PDE4 and mAKAPβ are nodal organizers of β2-ARs nuclear PKA signaling in cardiac myocytes

17.30-17-45        Flash presentations 2 (5 x 3’ talks)

17.45-18.10        Chat rooms session 2


18.10-19.00        Keynote lecture 1: Michel Bouvier (Université de Montréal, Canada)

Day 2

Session 3: Drug discovery I            Chair: Hélène Castel-Gandolfo & Frédéric Jean-Alphonse

14.00-14.20        Rachel Friedman Ohana, (Pomega corporation, USA) TBD

14.20-14.40        Laura Bohn (Scripps, USA) Toward Directing Opioid Receptor Signaling to Refine Opioid Therapeutics

14.40-15.00        Jean-Marc Devaud (Toulouse, France) Targeting an allatostatin receptor, a potential mediator of stress response in honey bees

15.00-15.20        Jean-Luc Galzi

15.20-15.35        Flash presentations 3 (5 x 3’ talks)

15.35-16.00        Chat rooms session 3

Session 4: Drug discovery II           Chair: Séverine Morisset-Lopez & Eric Reiter

16.00-16.20        Ross Cheloha (Harvard, Boston, USA) Nanobody-drug-conjugate at PTHR

16.20-16.40        S.J. Hill (University of Nottingham,UK) CRISPR-Mediated Protein Tagging with Nanoluciferase to Investigate Native Chemokine Receptor Function and Conformational Changes

16.40-17.00        Philippe Rondard (IGF, Montpellier, France) Nanobodies mGluR

17.00-17.20        Géraldine Schlecht-Louf (This email address is being protected from spambots. You need JavaScript enabled to view it.) CXCR4 signaling controls dendritic cell location and activation at steady-state and in inflammation

17.20-17.35        Flash presentations 4 (5 x 3’ talks)

17.35-18.00        Chat rooms session 4


18.00-18.50        Keynote lecture 2

                                    Bryan L. Roth (Univ North Carolina, USA)


Day 3

Session 5: Metabolism, Microbiome                         Chair: Pablo Chamero & Eric Reiter

14.00-14.20        Thue W Schwartz (The Panum Institute, Copenhagen, Denmark) Enterochromaffin 5-HT Cells - A Major Target for GLP-1 and Gut Microbial Metabolites

14.20-14.40        Graeme Milligan (University of Glasgow, Glasgow, UK) Short chain free fatty acids receptor

14.40-15.00        François Trottein (Pasteur Lille, France) Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production

15.00-15.20        Jacques Pantel (INSERM, Paris, France) Input of ghrelin receptor mutations in today’s understanding of the ghrelin system

15.20-15.35        Flash presentations 5 (5 x 3’ talks)

15.35-16.00        Chat rooms session 5


Session 6: Neurobiology, sensory biology               Chair: Lucie Pellissier & Pablo Chamero

16.00-16.20        Hiro Matsunami (Duke University, USA): Odorant receptors

16.20-16.40        Jianfeng Liu (or somebody from his lab) (Wuhan, China) A Cold-Sensing Receptor Encoded by a Glutamate Receptor Gene

16.40-17.00        Christophe Rochais (Caen, France) 5HTR ligand and Alzheimer

17.00-17.20        Pascal Dournaud (INSERM, Paris, France) A simple novel approach for detecting blood-brain barrier permeability using GPCR internalization

17.20-17.35        Flash presentations 6 (5 x 3’ talks)

17.35-18.00        Chat rooms session 6


18.00-18.50        Keynote lecture 3

                                    Valery Grinevich (Zentralinstitut für Seelische Gesundheit, Mannheim, Germany)


Day 4

Session 7: Structural biology                          Chair : Pascale Crépieux & Anne Poupon

14.00-14.20        Martha Sommer

14.20-14.40        Martin J Lohse (Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany): Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement

14.40-15.00        Bernard Mouillac (IGF, Montpellier, France): Cryo-EM structure of the vasopressin hormone-V2 receptor-Gs protein ternary complex

15.00-15.20        Esther Kellenberger (University of Strasbourg, France): Structure function relationships of CCR5

15.20-15.35        Flash presentations 7 (5 x 3’ talks)

15.35-16.00        Chat rooms session 7


Session 8: Computational approaches     Chair : Pascale Crépieux & Romain Yvinec

16.00-16.20        David E. Gloriam (University of Copenhagen, Copenhagen, Denmark) Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors

16.20-16.40        Graham Ladds ( University of Cambridge, UK) Engineering a Model Cell for Rational Tuning of GPCR Signaling

16.40-17.00        Romain Yvinec (INRAE Nouzilly, France) Mathematical modeling of GPCR-induced signaling.

17.00-17.20        Hughes Berry

17.20-17.35        Flash presentations 8 (5 x 3’ talks)

17.35-18.00        Chat rooms session 8


18.00-18.50        Keynote lecture 4

                                    Brian Kobilka (Stanford University, USA)


18.50-19.50        Awards & conclusions



Download this file (flyer final.pdf)flyer final.pdf[ ]737 kB

Virtual workshop on November 5th, 2020 from 1.30-5.30 pm.

on 18 September 2020

Scope of the 2020 Workshop: ‘bioinformatics and biomathematical approaches to integrate the GPCR signal’. Computational and mathematical approaches are nowadays compulsory in order to decipher the complexity of GPCR signalling networks. The workshop will focus on recent modelling and computational approaches and how they can be used to tackle GPCR complexity.


Virtual workshop on November 5th, 2020 from 1.30-5.30 pm.     To register please fill the form at the bottom

Participants: max 20 GDR ECI + 20 ERNEST/IRN ECI

Chair-women: Erika Cecon and Lucie Pellissier


  • 30 p.m. Ask the experts: Questions about omics, systems biology, machine learning that participants may have met with their experiments or simply want to ask (pre-recorded by volunteer participants in order to orientate the speakers’ presentations or text question on a slide with name and full affiliation).


  • 2 p.m. Dynamical modeling of reaction networks and biased signaling, Romain Yvinec (40min + 10min discussion/chat)

The purpose of this presentation will be to address how biomathematical approaches help deciphering kinetic and biased signalling.


  • 50 p.m. Extracting biological knowledge from omics datasets with Cytoscape, Pascale Crépieux (40min + 10min discussion/chat)

Cytoscape is an open source platform to analyze omic data. A demonstration of its potential will be presented using the RFSH signalling network as an example.


  • 40 p.m. GPCRmd uncovers the dynamics of the 3D-GPCRome Jana Selent, vice-chair of ERNEST COST (40min + 10min discussion/chat)


  • 30 p.m. GPCR Tracer discovery workflow using machine learning, late-stage chemistries, and BRET screening, Rachel Friedman Ohana and Mike Killoran (research collaboration with Promega; 30min + 15min discussion/chat)


  • 15 p.m. “Meet the speakers”: 4 dedicated parallel chat rooms of 10 participants max with each speaker (preference order made at the registration) – 15 min


Registration form

Global informations

4 dedicated parallel chat rooms with each speaker will be openned to talk with them for 15 min

10 people max per room (preference order made at the registration)

Please confirm that you are not a machine before submit
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GDR3545 Early Career Researchers Session in the 3rd ERNEST GPCR Meeting

on 15 September 2020

The annual congress of the European Research Network on Signal Transduction (ERNEST) has invited the GDR-3545 to organize a virtual session with early career researchers from the GDR the 14th October from 10h45 to 12h05.

Link for registration:
Link for abstract submission:


Cell Bio Virtual 2020

on 04 September 2020

Cell Bio Virtual 2020 Registration

is Now Open!

Connect Virtually From Wherever You Are

The joint meeting of the American Society for Cell Biology (ASCB) and the European Molecular Biology Organization (EMBO) takes cell biology to the virtual stage. Taking place December 2-16, 2020, the meeting will maintain cutting-edge cell biology as its core focus, along with interdisciplinary programming—giving attendees a place to learn from and collaborate with top researchers in their specific research area.

2020 Virtual Program Includes:

December 2-4
  • Education and Professional Development Sessions
December 7-11
  • Scientific Sessions
    • Keynote
    • Symposia
    • Minisymposia
    • Special Interest Subgroups
    • Major Award Lectures
December 14-16
  • Poster Sessions
Dates Coming Soon...
  • Tech Talks
  • Virtual Exhibit Hall

Registration/Abstract Deadlines

Sept. 2 - Poster presentations only (discounted)
Sept. 30 - Early bird registration deadline
Oct. 7 - Final abstract deadline (posters only)
 Registration Cell Bio 2020